Burkholderia cenocepacia J2315, BCAM2056 (bcscS)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM2056
NCBI Locus Tag	QU43_RS64640
Name	bcscS
Replicon	chromosome 2
Genomic location	2287737 - 2288015 (- strand)

Cross-References

RefSeq	WP_006480854.1
GI	206563897
Entrez	6930382
GI	206563897
INSDC	CAR55915.1
NCBI Locus Tag	QU43_RS64640
NCBI Old Locus Tag	BCAM2056
RefSeq	WP_006480854.1,GeneID
UniParc	UPI0000005455
UniProtKB Acc	B4EN99
UniProtKB ID	B4EN99_BURCJ
UniRef100	UniRef100_Q8VP22
UniRef50	UniRef50_B3RAD7
UniRef90	UniRef90_Q8VP22

Product

Feature Type	CDS
Coding Frame	1
Product Name	type III secretion system protein
Synonyms
Evidence for Translation
Charge (pH 7)	-0.02
Kyte-Doolittle Hydrophobicity Value	1.333
Molecular Weight (kDa)	9729.7
Isoelectric Point (pI)	6.62

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 215 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003803 (580 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM2056 Search term: bcscS Search term: type III secretion system protein

Human Homologs

References

A putative type III secretion gene cluster is widely distributed in the Burkholderia cepacia complex but absent from genomovar I. Parsons YN, Glendinning KJ, Thornton V, Hales BA, Hart CA, Winstanley C FEMS Microbiol Lett 2001 Sep 11;203(1):103-8 PubMed ID: 11557147

Sequence divergence in type III secretion gene clusters of the Burkholderia cepacia complex. Glendinning KJ, Parsons YN, Duangsonk K, Hales BA, Humphreys D, Hart CA, Winstanley C FEMS Microbiol Lett 2004 Jun 15;235(2):229-35 PubMed ID: 15183868