Burkholderia cenocepacia J2315, BCAM2050 (bcscK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM2050
NCBI Locus TagQU43_RS64610
Name
bcscK
Replicon chromosome 2
Genomic location 2281742 - 2282482 (- strand)

Cross-References

RefSeq WP_012493470.1
GI 206563891
Entrez 6930386
GI 206563891
INSDC CAR55909.1
NCBI Locus Tag QU43_RS64610
NCBI Old Locus Tag BCAM2050
RefSeq WP_012493470.1,GeneID
UniParc UPI000000545A
UniProtKB Acc B4EN93
UniProtKB ID B4EN93_BURCJ
UniRef100 UniRef100_Q8VP17
UniRef50 UniRef50_Q8VP17
UniRef90 UniRef90_Q8VP17

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system protein
Synonyms
Evidence for Translation
Charge (pH 7) 1.62
Kyte-Doolittle Hydrophobicity Value -0.004
Molecular Weight (kDa) 27054.7
Isoelectric Point (pI) 7.71

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 3 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003798 (248 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM2050
Search term: bcscK

Human Homologs

References

A putative type III secretion gene cluster is widely distributed in the Burkholderia cepacia complex but absent from genomovar I.
Parsons YN, Glendinning KJ, Thornton V, Hales BA, Hart CA, Winstanley C
FEMS Microbiol Lett 2001 Sep 11;203(1):103-8
PubMed ID: 11557147
Sequence divergence in type III secretion gene clusters of the Burkholderia cepacia complex.
Glendinning KJ, Parsons YN, Duangsonk K, Hales BA, Humphreys D, Hart CA, Winstanley C
FEMS Microbiol Lett 2004 Jun 15;235(2):229-35
PubMed ID: 15183868