Burkholderia cenocepacia J2315, BCAM2049 (bcscL)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM2049
NCBI Locus Tag	QU43_RS64605
Name	bcscL
Replicon	chromosome 2
Genomic location	2281131 - 2281760 (- strand)

Cross-References

RefSeq	WP_006487566.1
GI	206563890
Entrez	6930387
GI	206563890
INSDC	CAR55908.1
NCBI Locus Tag	QU43_RS64605
NCBI Old Locus Tag	BCAM2049
RefSeq	WP_006487566.1,GeneID
UniParc	UPI000000545B
UniProtKB Acc	B4EN92
UniProtKB ID	B4EN92_BURCJ
UniRef100	UniRef100_Q83WB1
UniRef50	UniRef50_A0A071M9R5
UniRef90	UniRef90_A0A071M9R5

Product

Feature Type	CDS
Coding Frame	1
Product Name	type III secretion system protein
Synonyms
Evidence for Translation
Charge (pH 7)	-0.55
Kyte-Doolittle Hydrophobicity Value	-0.260
Molecular Weight (kDa)	23010.9
Isoelectric Point (pI)	6.56

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 31 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003797 (251 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM2049 Search term: bcscL Search term: type III secretion system protein

Human Homologs

References

A putative type III secretion gene cluster is widely distributed in the Burkholderia cepacia complex but absent from genomovar I. Parsons YN, Glendinning KJ, Thornton V, Hales BA, Hart CA, Winstanley C FEMS Microbiol Lett 2001 Sep 11;203(1):103-8 PubMed ID: 11557147

Sequence divergence in type III secretion gene clusters of the Burkholderia cepacia complex. Glendinning KJ, Parsons YN, Duangsonk K, Hales BA, Humphreys D, Hart CA, Winstanley C FEMS Microbiol Lett 2004 Jun 15;235(2):229-35 PubMed ID: 15183868