Burkholderia cenocepacia J2315, BCAM2048 (bcscN)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM2048
NCBI Locus Tag	QU43_RS64600
Name	bcscN
Replicon	chromosome 2
Genomic location	2279761 - 2281134 (- strand)

Cross-References

RefSeq	WP_006487564.1
GI	206563889
Entrez	6929667
GI	206563889
INSDC	CAR55907.1
NCBI Locus Tag	QU43_RS64600
NCBI Old Locus Tag	BCAM2048
RefSeq	WP_006487564.1,GeneID
UniParc	UPI000000545C
UniProtKB Acc	B4EN91
UniProtKB ID	B4EN91_BURCJ
UniRef100	UniRef100_Q8VP15
UniRef50	UniRef50_P40291
UniRef90	UniRef90_Q1BPP2

Product

Feature Type	CDS
Coding Frame	1
Product Name	type III secretion ssytem protein
Synonyms
Evidence for Translation
Charge (pH 7)	-3.87
Kyte-Doolittle Hydrophobicity Value	-0.008
Molecular Weight (kDa)	48935.3
Isoelectric Point (pI)	6.26

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 666 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003796 (728 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM2048 Search term: bcscN Search term: type III secretion ssytem protein

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000262030 ATP synthase F1 subunit beta [Source:HGNC Symbol;Acc:HGNC:830] E-value: 6.3e-34 Percent Identity: 28.8

References

A putative type III secretion gene cluster is widely distributed in the Burkholderia cepacia complex but absent from genomovar I. Parsons YN, Glendinning KJ, Thornton V, Hales BA, Hart CA, Winstanley C FEMS Microbiol Lett 2001 Sep 11;203(1):103-8 PubMed ID: 11557147

Sequence divergence in type III secretion gene clusters of the Burkholderia cepacia complex. Glendinning KJ, Parsons YN, Duangsonk K, Hales BA, Humphreys D, Hart CA, Winstanley C FEMS Microbiol Lett 2004 Jun 15;235(2):229-35 PubMed ID: 15183868