Burkholderia cenocepacia J2315, BCAM1007 (bceQ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM1007
NCBI Locus TagQU43_RS59415
Name
bceQ
Replicon chromosome 2
Genomic location 1117023 - 1118489 (+ strand)
CommentMember of the bce-II gene cluster
CommentDisruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis

Cross-References

RefSeq WP_006491256.1
GI 206562862
Entrez 6928715
GI 206562862
INSDC CAR54864.1
NCBI Locus Tag QU43_RS59415
NCBI Old Locus Tag BCAM1007
RefSeq WP_006491256.1,GeneID
UniParc UPI00017B9D26
UniProtKB Acc B4EFL5
UniProtKB ID B4EFL5_BURCJ
UniRef100 UniRef100_A0A095E907
UniRef50 UniRef50_Q13YU9
UniRef90 UniRef90_Q393Z3

Product

Feature Type CDS
Coding Frame 1
Product Name
putative polysaccharide biosynthesis protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 11.88
Kyte-Doolittle Hydrophobicity Value 0.853
Molecular Weight (kDa) 52443.7
Isoelectric Point (pI) 10.22

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 55 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003105 (651 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM1007
Search term: bceQ

Human Homologs

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863