Burkholderia cenocepacia J2315, BCAL3120 (wbiH)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL3120
NCBI Locus Tag	QU43_RS52330
Name	wbiH
Replicon	chromosome 1
Genomic location	3411022 - 3412038 (- strand)
Comment	Belongs to the O antigen biosynthesis gene cluster

Cross-References

RefSeq	WP_012492902.1
GI	206561466
Entrez	6934242
GI	206561466
INSDC	CAR53444.1
NCBI Locus Tag	QU43_RS52330
NCBI Old Locus Tag	BCAL3120
RefSeq	WP_012492902.1,GeneID
UniParc	UPI00017B9957
UniProtKB Acc	B4ECE1
UniProtKB ID	B4ECE1_BURCJ
UniRef100	UniRef100_B4ECE1
UniRef50	UniRef50_Q39IY4
UniRef90	UniRef90_B4ECE1

Product

Feature Type	CDS
Coding Frame	1
Product Name	UDP-N-acetylglucosamine-1-P transferase Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7)	9.64
Kyte-Doolittle Hydrophobicity Value	0.646
Molecular Weight (kDa)	36916.1
Isoelectric Point (pI)	10.39

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 468 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000741 (647 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL3120 Search term: wbiH Search term: UDP-N-acetylglucosamine-1-P transferase

Human Homologs

References

Reconstitution of O-specific lipopolysaccharide expression in Burkholderia cenocepacia strain J2315, which is associated with transmissible infections in patients with cystic fibrosis. Ortega X, Hunt TA, Loutet S, Vinion-Dubiel AD, Datta A, Choudhury B, Goldberg JB, Carlson R, Valvano MA J Bacteriol 2005 Feb;187(4):1324-33 PubMed ID: 15687196