Burkholderia cenocepacia J2315, BCAL2200 (bptpA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2200
NCBI Locus TagQU43_RS47610
Name
bptpA
Replicon chromosome 1
Genomic location 2427399 - 2427881 (- strand)

Cross-References

RefSeq WP_006481978.1
GI 206560562
Entrez 6932320
GI 206560562
INSDC CAR52501.1
NCBI Locus Tag QU43_RS47610
NCBI Old Locus Tag BCAL2200
RefSeq WP_006481978.1,GeneID
UniParc UPI00017B93E8
UniProtKB Acc B4EDS9
UniProtKB ID B4EDS9_BURCJ
UniRef100 UniRef100_B4EDS9
UniRef50 UniRef50_A9AGU1
UniRef90 UniRef90_A9AGU1

Product

Feature Type CDS
Coding Frame 1
Product Name
Burkholderia phosphotyrosine phosphatase, BPtpA
Product Name Confidence: Class 1
Synonyms Low molecular weight protein tyrosine phosphatase, class II.I
Evidence for Translation
Charge (pH 7) -2.44
Kyte-Doolittle Hydrophobicity Value -0.232
Molecular Weight (kDa) 17499.6
Isoelectric Point (pI) 5.73

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 406 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002021 (651 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2200
Search term: bptpA

References

The BPtpA protein from Burkholderia cenocepacia belongs to a new subclass of low molecular weight protein tyrosine phosphatases.
Sánchez-Rodríguez R, González GM, Becerril-García MA, Treviño-Rangel RJ, Marcos-Vilchis A, González-Pedrajo B, Valvano MA, Andrade A
Arch Biochem Biophys 2020 Mar 15;681:108277
PubMed ID: 31978399