Burkholderia multivorans ATCC 17616, BMULJ_RS27615 (ampC1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia multivorans ATCC 17616 - Assembly GCF_000010545.1
GCF_000010545.1|latest
Locus Tag
BMULJ_RS27615
Name
ampC1
Synonym: ampC
Replicon chromosome 3
Genomic location 179035 - 180204 (+ strand)
CommentAmpC1 from B. multivorans ATCC 17616 possesses a narrow spectrum, and the contribution of AmpC1 to _-lactam resistance appears to be negligible, yet expression of AmpC1 is regulated by _-lactam inducers including imipenem (PMID:30012762).

Cross-References

RefSeq WP_012218336.1
GI 0

Product

Feature Type CDS
Coding Frame 1
Product Name
class C beta-lactamase
Product Name Confidence: Class 2
Evidence for Translation
Charge (pH 7) 9.19
Kyte-Doolittle Hydrophobicity Value 0.015
Molecular Weight (kDa) 41875.9
Isoelectric Point (pI) 9.89

Subcellular localization

Individual Mappings
Localization Confidence PMID
Additional evidence for subcellular localization

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMULJ_RS27615
Search term: ampC1

References

Characterization of the AmpC beta-Lactamase from Burkholderia multivorans.
Becka SA, Zeiser ET, Barnes MD, Taracila MA, Nguyen K, Singh I, Sutton GG, LiPuma JJ, Fouts DE, Papp-Wallace KM
Antimicrob Agents Chemother 2018 Oct;62(10)
PubMed ID: 30012762