Burkholderia pseudomallei K96243, BPSS2335 (glnQ)

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSS2335
Name	glnQ
Replicon	chromosome 2
Genomic location	3150721 - 3151443 (- strand)

Cross-References

RefSeq	YP_112337.1
GI	53723352
Entrez	3095798
GI	53723352
INSDC	CAH39821.1
NCBI Locus Tag	BPSS2335
RefSeq	YP_112337.1,GeneID
UniParc	UPI000043C038
UniProtKB Acc	Q63HT5
UniProtKB ID	Q63HT5_BURPS
UniRef100	UniRef100_A1UXM0
UniRef50	UniRef50_P10346
UniRef90	UniRef90_A1UXM0

Product

Feature Type	CDS
Coding Frame	1
Product Name	glutamine ABC transporter ATP-binding protein
Synonyms
Evidence for Translation
Charge (pH 7)	2.65
Kyte-Doolittle Hydrophobicity Value	-0.006
Molecular Weight (kDa)	26112.2
Isoelectric Point (pI)	8.52

Subcellular localization

Individual Mappings	Localization Confidence PMID Extracellular Class 1 quantitative mass spectrometry evidence 25635268 Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000551 (989 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSS2335 Search term: glnQ Search term: glutamine ABC transporter ATP-binding protein

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000265724 ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40] E-value: 6.3e-25 Percent Identity: 35.8
Ensembl 97, assembly GRCh38.p12	ENSP00000444095 ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40] E-value: 6.3e-25 Percent Identity: 35.8
Ensembl 97, assembly GRCh38.p12	ENSP00000478255 ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40] E-value: 6.3e-25 Percent Identity: 35.8

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants. Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM Mol Cell Proteomics 2015 Apr;14(4):905-16 PubMed ID: 25635268