Burkholderia pseudomallei K96243, BPSS2102 (TagE-6)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS2102
Name
TagE-6
Replicon chromosome 2
Genomic location 2843816 - 2846431 (- strand)

Cross-References

RefSeq YP_112101.1
GI 53723116
Entrez 3095433
GI 53723116
INSDC CAH39582.1
NCBI Locus Tag BPSS2102
RefSeq YP_112101.1,GeneID
UniParc UPI000043BF4C
UniProtKB Acc Q63IH1
UniProtKB ID Q63IH1_BURPS
UniRef100 UniRef100_Q63IH1
UniRef50 UniRef50_A1UYY9
UniRef90 UniRef90_Q3JJ94

Product

Feature Type CDS
Coding Frame 1
Product Name
protein kinase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -14.91
Kyte-Doolittle Hydrophobicity Value -0.406
Molecular Weight (kDa) 89878.5
Isoelectric Point (pI) 5.46

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 403 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG016589 (492 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS2102
Search term: TagE-6
Search term: protein kinase

Human Homologs

Ensembl 97, assembly GRCh38.p12
CDC42 binding protein kinase alpha [Source:HGNC Symbol;Acc:HGNC:1737]
E-value: 4.0e-13
Percent Identity: 31.1
Ensembl 97, assembly GRCh38.p12
CDC42 binding protein kinase alpha [Source:HGNC Symbol;Acc:HGNC:1737]
E-value: 4.0e-13
Percent Identity: 31.1
Ensembl 97, assembly GRCh38.p12
CDC42 binding protein kinase alpha [Source:HGNC Symbol;Acc:HGNC:1737]
E-value: 4.0e-13
Percent Identity: 31.1
Ensembl 97, assembly GRCh38.p12
CDC42 binding protein kinase alpha [Source:HGNC Symbol;Acc:HGNC:1737]
E-value: 4.0e-13
Percent Identity: 31.1

References

In vivo expression technology identifies a type VI secretion system locus in Burkholderia pseudomallei that is induced upon invasion of macrophages.
Shalom G, Shaw JG, Thomas MS
Microbiology 2007 Aug;153(Pt 8):2689-2699
PubMed ID: 17660433