Burkholderia pseudomallei K96243, BPSS1993 (mprA)

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSS1993
Name	mprA
Replicon	chromosome 2
Genomic location	2695482 - 2696984 (- strand)

Cross-References

RefSeq	YP_111999.1
GI	53723014
Entrez	3095199
GI	53723014
INSDC	CAH39471.1
NCBI Locus Tag	BPSS1993
RefSeq	YP_111999.1,GeneID
UniParc	UPI00000B91A8
UniProtKB Acc	H7C763
UniProtKB ID	H7C763_BURPS
UniRef100	UniRef100_Q9F881
UniRef50	UniRef50_A3NND2
UniRef90	UniRef90_A3P8S9

Product

Feature Type	CDS
Coding Frame	1
Product Name	serine metalloprotease precursor
Synonyms
Evidence for Translation
Charge (pH 7)	1.23
Kyte-Doolittle Hydrophobicity Value	0.009
Molecular Weight (kDa)	50234.6
Isoelectric Point (pI)	7.43

Subcellular localization

Individual Mappings	Localization Confidence PMID Extracellular Class 1 quantitative mass spectrometry evidence 25635268 Extracellular Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 369 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG021020 (426 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSS1993 Search term: mprA Search term: serine metalloprotease precursor

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants. Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM Mol Cell Proteomics 2015 Apr;14(4):905-16 PubMed ID: 25635268