Burkholderia pseudomallei K96243, BPSS1831 (bceE)

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSS1831
Name	bceE
Replicon	chromosome 2
Genomic location	2491078 - 2492253 (- strand)
Comment	Member of the bce-I gene cluster

Cross-References

RefSeq	YP_111835.1
GI	53722850
Entrez	3095991
GI	53722850
INSDC	CAH39307.1
NCBI Locus Tag	BPSS1831
RefSeq	YP_111835.1,GeneID
UniParc	UPI000043BE44
UniProtKB Acc	Q63J87
UniProtKB ID	Q63J87_BURPS
UniRef100	UniRef100_Q3JK30
UniRef50	UniRef50_Q3JK30
UniRef90	UniRef90_Q3JK30

Product

Feature Type	CDS
Coding Frame	1
Product Name	BceE Product Name Confidence: Class 2
Synonyms	exopolysaccharide (EPS) biosynthesis related polysaccharide lipoprotein
Evidence for Translation	Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724). Found in at least two preparations.
Charge (pH 7)	2.69
Kyte-Doolittle Hydrophobicity Value	-0.222
Molecular Weight (kDa)	42655.3
Isoelectric Point (pI)	8.78

Subcellular localization

Individual Mappings	Localization Confidence PMID Outer Membrane Class 3 20472543 Extracellular Class 1 quantitative mass spectrometry evidence 25635268
Additional evidence for subcellular localization	Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 302 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG004850 (650 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSS1831 Search term: bceE Search term: BceE

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants. Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM Mol Cell Proteomics 2015 Apr;14(4):905-16 PubMed ID: 25635268

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions. Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM Appl Environ Microbiol 2010 Jan;76(2):441-50 PubMed ID: 19948863