Burkholderia pseudomallei K96243, BPSS1742

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1742
Name
Replicon chromosome 2
Genomic location 2391608 - 2393857 (- strand)

Cross-References

RefSeq YP_111748.1
GI 53722763
Entrez 3097071
GI 53722763
INSDC CAH39217.1
NCBI Locus Tag BPSS1742
RefSeq YP_111748.1,GeneID
UniParc UPI000043BDED
UniProtKB Acc Q63JH4
UniProtKB ID Q63JH4_BURPS
UniRef100 UniRef100_A0A089B297
UniRef50 UniRef50_Q88DI7
UniRef90 UniRef90_Q2T7L2

Product

Feature Type CDS
Coding Frame 1
Product Name
outer membrane copper receptor
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724). Found in at least two preparations.
Charge (pH 7) 11.35
Kyte-Doolittle Hydrophobicity Value -0.359
Molecular Weight (kDa) 80457.6
Isoelectric Point (pI) 9.49

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Outer Membrane Class 3
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 193 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003049 (620 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1742

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268