Strain |
Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest |
Locus Tag |
BPSS0095
|
Name |
tssL-2a
|
Replicon | chromosome 2 |
Genomic location | 115016 - 115672 (+ strand) |
Comment | Gene is part of a cluster known as the type VI secretion system gene cluster tss-2 used in much of the early P. pseudomallei literature (PMID:17660433) but later referred to as T6SS-5 cluster later (PMID:22007185) |
RefSeq | YP_110118.1 |
GI | 53721133 |
Entrez | 3096792 |
GI | 53721133 |
NCBI Locus Tag | BPSS0095 |
RefSeq | YP_110118.1,GeneID |
UniProtKB Acc | Q63P51 |
UniProtKB ID | Q63P51_BURPS |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
type VI secretion system-associated protein TssL-2a
|
Synonyms |
hypothetical protein |
Evidence for Translation | |
Charge (pH 7) | -1.93 |
Kyte-Doolittle Hydrophobicity Value | -0.196 |
Molecular Weight (kDa) | 24259.4 |
Isoelectric Point (pI) | 6.60 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 5 genera
|
Burkholderia Ortholog Group |
BG020407 (319 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BPSS0095
Search term: tssL-2a
Search term: type VI secretion system-associated protein TssL-2a
|
In vivo expression technology identifies a type VI secretion system locus in Burkholderia pseudomallei that is induced upon invasion of macrophages.
Shalom G, Shaw JG, Thomas MS
Microbiology 2007 Aug;153(Pt 8):2689-2699
PubMed ID: 17660433
|
Strategies for Intracellular Survival of Burkholderia pseudomallei.
Allwood EM, Devenish RJ, Prescott M, Adler B, Boyce JD
Front Microbiol 2011;2:170
PubMed ID: 22007185
|
Type VI secretion is a major virulence determinant in Burkholderia mallei.
Schell MA, Ulrich RL, Ribot WJ, Brueggemann EE, Hines HB, Chen D, Lipscomb L, Kim HS, Mrázek J, Nierman WC, Deshazer D
Mol Microbiol 2007 Jun;64(6):1466-85
PubMed ID: 17555434
|