Burkholderia pseudomallei K96243, BPSL2063 (bpaB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2063
Name
bpaB
Replicon chromosome 1
Genomic location 2467978 - 2471250 (- strand)

Cross-References

RefSeq YP_108662.1
GI 53719676
Entrez 3093202
GI 53719676
INSDC CAH36064.1
NCBI Locus Tag BPSL2063
RefSeq YP_108662.1,GeneID
UniParc UPI000043B237
UniProtKB Acc Q63TA4
UniProtKB ID Q63TA4_BURPS
UniRef100 UniRef100_A0A095RZT5
UniRef50 UniRef50_A3MIX4
UniRef90 UniRef90_A3MIX4

Product

Feature Type CDS
Coding Frame 1
Product Name
putative trimeric autoransporter, BpaB
Product Name Confidence: Class 2
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) -11.84
Kyte-Doolittle Hydrophobicity Value -0.021
Molecular Weight (kDa) 105427.4
Isoelectric Point (pI) 4.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4USX TRANSPORT PROTEIN 07/16/14 The Structure of the C-terminal YadA-like domain of BPSL2063 from Burkholderia pseudomallei BURKHOLDERIA PSEUDOMALLEI K96243 1.8 X-RAY DIFFRACTION 98.3

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 68 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG017641 (35 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2063
Search term: bpaB

Human Homologs

References

Functional characterization of Burkholderia pseudomallei trimeric autotransporters.
Campos CG, Byrd MS, Cotter PA
Infect Immun 2013 Aug;81(8):2788-99
PubMed ID: 23716608