Strain |
Burkholderia cenocepacia J2315
GCF_000009485.1|latest |
Locus Tag |
BCAL1536
|
NCBI Locus Tag | QU43_RS44190 |
Name |
rpoN
|
Replicon | chromosome 1 |
Genomic location | 1701800 - 1703191 (+ strand) |
RefSeq | WP_006483492.1 |
GI | 206559902 |
Entrez | 6931811 |
GI | 206559902 |
INSDC | CAR51835.1 |
NCBI Locus Tag | QU43_RS44190 |
NCBI Old Locus Tag | BCAL1536 |
RefSeq | WP_006483492.1,GeneID |
UniParc | UPI00017B948D |
UniProtKB Acc | B4E832 |
UniProtKB ID | B4E832_BURCJ |
UniRef100 | UniRef100_A0A095DR90 |
UniRef50 | UniRef50_I9BST1 |
UniRef90 | UniRef90_C5AGX4 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
alternative sigma factor RpoN
|
Synonyms |
putative sigma-54 related transcriptional regulatory protein |
Evidence for Translation | |
Charge (pH 7) | -10.21 |
Kyte-Doolittle Hydrophobicity Value | -0.155 |
Molecular Weight (kDa) | 51487.1 |
Isoelectric Point (pI) | 5.51 |
Individual Mappings | |
Additional evidence for subcellular localization |
Source 1 | |
Database | BGD |
Category | Alternative Sigma factors |
Evidence |
ECO:0000315
mutant phenotype evidence used in manual assertion
|
Host Organism | Rattus norvegicus |
Notes | rpoN mutant attenuated for virulence in agar bead model of chronic lung infection |
Reference | 15213146 |
Source 2 | |
Database | BGD |
Category | Alternative Sigma factors |
Evidence |
ECO:0000315
mutant phenotype evidence used in manual assertion
|
Host Organism | Mus musculus |
Notes | rpoN mutant cannot delay phagolysosomal fusion in mouse RAW 264.7 macrophages |
Reference | 18195023 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 427 genera
|
Burkholderia Ortholog Group |
BG001356 (648 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BCAL1536
Search term: rpoN
Search term: alternative sigma factor RpoN
|
Identification of Burkholderia cenocepacia genes required for bacterial survival in vivo.
Hunt TA, Kooi C, Sokol PA, Valvano MA
Infect Immun 2004 Jul;72(7):4010-22
PubMed ID: 15213146
|
Burkholderia cenocepacia requires the RpoN sigma factor for biofilm formation and intracellular trafficking within macrophages.
Saldías MS, Lamothe J, Wu R, Valvano MA
Infect Immun 2008 Mar;76(3):1059-67
PubMed ID: 18195023
|