Burkholderia dolosa AU0158, AK34_RS07140 (bceC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003979 UDP-glucose 6-dehydrogenase activity
ISO
Inferred from Sequence Orthology
Term mapped from: GenBank:GQ451909.1
 ECO:0000266
sequence orthology evidence used in manual assertion		 21602353 Reviewed by curator
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00984
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00984
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00984
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003979 UDP-glucose 6-dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF500134
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000271 polysaccharide biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF500134
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc UDP-α-D-glucuronate biosynthesis (from UDP-glucose) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00053 Ascorbate and aldarate metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00520 Amino sugar and nucleotide sugar metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc teichuronic acid biosynthesis (<i>B. subtilis</i> 168) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00040 Pentose and glucuronate interconversions InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PIRSF PIRSF500134 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type 1 454 3.8E-189
Gene3D G3DSA:3.40.50.720 1 206 2.4E-89
SUPERFAMILY SSF48179 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily 208 305 2.72E-32
Gene3D G3DSA:1.20.5.100 207 238 2.5E-19
Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation 208 300 1.1E-37
SUPERFAMILY SSF51735 IPR036291 NAD(P)-binding domain superfamily 1 198 2.29E-56
Gene3D G3DSA:3.40.50.720 239 470 1.2E-92
PIRSF PIRSF000124 IPR017476 UDP-glucose/GDP-mannose dehydrogenase 1 451 1.5E-151
Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal 324 435 3.6E-31
SUPERFAMILY SSF52413 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily 309 446 4.71E-41
TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase IPR017476 UDP-glucose/GDP-mannose dehydrogenase 1 432 5.2E-134
Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal 1 186 8.9E-64
SMART SM00984 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal 324 436 1.9E-46

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.