Burkholderia cenocepacia J2315, BCAM0221

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
Locus Tag
BCAM0221
NCBI Locus TagQU43_RS55525
Name
Replicon chromosome 2
Genomic location 269146 - 269865 (+ strand)

Cross-References

RefSeq WP_006489563.1
GI 206562091
Entrez 6928016
GI 206562091
INSDC CAR54079.1
NCBI Locus Tag QU43_RS55525
NCBI Old Locus Tag BCAM0221
RefSeq WP_006489563.1,GeneID
UniParc UPI00017B9DBF
UniProtKB Acc B4EHQ3
UniProtKB ID B4EHQ3_BURCJ
UniRef100 UniRef100_B4EHQ3
UniRef50 UniRef50_B4EHQ3
UniRef90 UniRef90_B4EHQ3

Product

Feature Type CDS
Coding Frame 1
Product Name
two-component regulatory system response regulator protein
Synonyms
Evidence for Translation
Charge (pH 7) -4.14
Kyte-Doolittle Hydrophobicity Value 0.035
Molecular Weight (kDa) 25437.7
Isoelectric Point (pI) 6.09

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 465 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003783 (1065 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM0221

References

A BCAM0223 mutant of Burkholderia cenocepacia is deficient in hemagglutination, serum resistance, adhesion to epithelial cells and virulence.
Mil-Homens D, Fialho AM.
PLoS One. 2012;7(7):e41747.
PubMed ID: 22848588