Burkholderia multivorans ATCC 17616, Bmul_5122 (rpfR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia multivorans ATCC 17616 - Assembly GCF_000018505.1
Locus Tag
Bmul_5122
NCBI Locus TagBMUL_RS25815
Name
rpfR
Replicon chromosome 2
Genomic location 2260844 - 2262847 (- strand)

Cross-References

RefSeq WP_012217627.1
GI 161521657
Entrez 5769908
GI 161521657
NCBI Locus Tag BMUL_RS25815
NCBI Old Locus Tag Bmul_5122
RefSeq WP_012217627.1
UniProtKB Acc A9AQ19
UniProtKB ID A9AQ19_BURM1

Product

Feature Type CDS
Coding Frame 1
Product Name
cis-2-dodecenoic acid receptor RpfR
Product Name Confidence: Class 2
Synonyms RNase II stability modulator
Evidence for Translation
Charge (pH 7) -10.33
Kyte-Doolittle Hydrophobicity Value -0.045
Molecular Weight (kDa) 73310.6
Isoelectric Point (pI) 6.09

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 458 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004646 (511 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bmul_5122
Search term: rpfR

References

Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover.
Deng Y, Schmid N, Wang C, Wang J, Pessi G, Wu D, Lee J, Aguilar C, Ahrens CH, Chang C, Song H, Eberl L, Zhang LH.
Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15479-84.
PubMed ID: 22949660
PubMed ID: 28956352
PubMed ID: 28463102
PubMed ID: 23815566