Strain |
Burkholderia multivorans ATCC 17616 - Assembly GCF_000018505.1
GCF_000018505.1|latest |
Locus Tag |
Bmul_5122
|
NCBI Locus Tag | BMUL_RS25815 |
Name |
rpfR
|
Replicon | chromosome 2 |
Genomic location | 2260844 - 2262847 (- strand) |
RefSeq | WP_012217627.1 |
GI | 161521657 |
Entrez | 5769908 |
GI | 161521657 |
NCBI Locus Tag | BMUL_RS25815 |
NCBI Old Locus Tag | Bmul_5122 |
RefSeq | WP_012217627.1 |
UniProtKB Acc | A9AQ19 |
UniProtKB ID | A9AQ19_BURM1 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
cis-2-dodecenoic acid receptor RpfR
|
Synonyms |
RNase II stability modulator |
Evidence for Translation | |
Charge (pH 7) | -10.33 |
Kyte-Doolittle Hydrophobicity Value | -0.045 |
Molecular Weight (kDa) | 73310.6 |
Isoelectric Point (pI) | 6.09 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 458 genera
|
Burkholderia Ortholog Group |
BG004646 (511 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: Bmul_5122
Search term: rpfR
Search term: cis-2-dodecenoic acid receptor RpfR
|
Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover.
Deng Y, Schmid N, Wang C, Wang J, Pessi G, Wu D, Lee J, Aguilar C, Ahrens CH, Chang C, Song H, Eberl L, Zhang LH
Proc Natl Acad Sci U S A 2012 Sep 18;109(38):15479-84
PubMed ID: 22949660
|
Mutation of the cyclic di-GMP phosphodiesterase gene in Burkholderia lata SK875 attenuates virulence and enhances biofilm formation.
Jung HI, Kim YJ, Lee YJ, Lee HS, Lee JK, Kim SK
J Microbiol 2017 Oct;55(10):800-808
PubMed ID: 28956352
|
High intracellular c-di-GMP levels antagonize quorum sensing and virulence gene expression in Burkholderia cenocepacia H111.
Schmid N, Suppiger A, Steiner E, Pessi G, Kaever V, Fazli M, Tolker-Nielsen T, Jenal U, Eberl L
Microbiology 2017 May;163(5):754-764
PubMed ID: 28463102
|
Cis-2-dodecenoic acid quorum sensing system modulates N-acyl homoserine lactone production through RpfR and cyclic di-GMP turnover in Burkholderia cenocepacia.
Deng Y, Lim A, Wang J, Zhou T, Chen S, Lee J, Dong YH, Zhang LH
BMC Microbiol 2013 Jul 1;13:148
PubMed ID: 23815566
|