Burkholderia mallei ATCC 23344, BMAA1621
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia mallei ATCC 23344
GCF_000011705.1|latest |
| Locus Tag |
BMAA1621
|
| Name |
|
| Replicon | chromosome 2 |
| Genomic location | 1760032 - 1761465 (- strand) |
| Comment | This gene is part of the type III secretion system T3SS-2 locus found in B. malllei. |
Cross-References
| RefSeq | YP_106198.1 |
| GI | 53716452 |
| NCBI Locus Tag | BMAA1621 |
| RefSeq | YP_106198.1,GeneID |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
type III secretion system regulator (T3SS-2)
|
| Synonyms |
regulatory protein HrpB |
| Evidence for Translation | |
| Charge (pH 7) | 9.65 |
| Kyte-Doolittle Hydrophobicity Value | -0.203 |
| Molecular Weight (kDa) | 52290.4 |
| Isoelectric Point (pI) | 8.84 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results | Analysis not done |
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG017486 (471 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: BMAA1621
Search term: type III secretion system regulator (T3SS-2)
|
Human Homologs
References
|
Type III secretion system cluster 3 is required for maximal virulence of Burkholderia pseudomallei in a hamster infection model.
Warawa J, Woods DE
FEMS Microbiol Lett 2005 Jan 1;242(1):101-8
PubMed ID: 15621426
|
|
Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152
|