Burkholderia cenocepacia J2315, BCAM0904 (polA)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM0904
NCBI Locus Tag	QU43_RS58890
Name	polA
Replicon	chromosome 2
Genomic location	991830 - 994583 (+ strand)

Cross-References

RefSeq	WP_012493192.1
GI	206562759
Entrez	6928644
GI	206562759
INSDC	CAR54761.1
NCBI Locus Tag	QU43_RS58890
NCBI Old Locus Tag	BCAM0904
RefSeq	WP_012493192.1,GeneID
UniParc	UPI00017B9A8E
UniProtKB Acc	B4EN22
UniProtKB ID	B4EN22_BURCJ
UniRef100	UniRef100_B4EN22
UniRef50	UniRef50_Q9HT80
UniRef90	UniRef90_G7HFQ5

Product

Feature Type	CDS
Coding Frame	1
Product Name	DNA polymerase I
Synonyms
Evidence for Translation
Charge (pH 7)	-26.99
Kyte-Doolittle Hydrophobicity Value	-0.224
Molecular Weight (kDa)	101083.3
Isoelectric Point (pI)	5.05

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 592 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003011 (659 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM0904 Search term: polA Search term: DNA polymerase I

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000435506 DNA polymerase nu [Source:HGNC Symbol;Acc:HGNC:18870] E-value: 4.9e-54 Percent Identity: 31.7
Ensembl 97, assembly GRCh38.p12	ENSP00000372316 DNA polymerase nu [Source:HGNC Symbol;Acc:HGNC:18870] E-value: 4.9e-54 Percent Identity: 31.7

References