Burkholderia cenocepacia J2315, BCAS0729 (deoA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004645 phosphorylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000478
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006213 pyrimidine nucleoside metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02643
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0009032 thymidine phosphorylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02643
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016757 transferase activity, transferring glycosyl groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00591
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016154 pyrimidine-nucleoside phosphorylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02644
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006206 pyrimidine nucleobase metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00647
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016763 transferase activity, transferring pentosyl groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00941
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj00240 Pyrimidine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00983 Drug metabolism - other enzymes InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleosides degradation InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00240 Pyrimidine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.90.1170.30 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily 337 432 5.8E-28
Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal 350 422 8.4E-20
Pfam PF02885 Glycosyl transferase family, helical bundle domain IPR017459 Glycosyl transferase family 3, N-terminal domain 6 67 3.6E-15
TIGRFAM TIGR02643 T_phosphoryl: thymidine phosphorylase IPR013465 Thymidine phosphorylase 2 428 6.9E-215
SMART SM00941 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal 350 424 3.3E-25
PIRSF PIRSF000478 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase 1 437 4.6E-150
TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic 5 421 1.2E-152
ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site 113 128 -
Gene3D G3DSA:3.40.1030.10 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily 70 322 3.3E-122
SUPERFAMILY SSF52418 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily 73 332 1.06E-87
Gene3D G3DSA:1.20.970.10 8 195 3.3E-122
SUPERFAMILY SSF54680 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily 337 433 1.96E-27
Pfam PF00591 Glycosyl transferase family, a/b domain IPR000312 Glycosyl transferase, family 3 80 309 5.7E-41
Hamap MF_01628 Thymidine phosphorylase [deoA]. IPR013465 Thymidine phosphorylase 2 437 46.626
SUPERFAMILY SSF47648 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily 2 70 1.57E-18

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.