Burkholderia cenocepacia J2315, BCAS0228

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.90.15.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003917 DNA topoisomerase type I activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.90.15.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006265 DNA topological change
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.90.15.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.90.15.10 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type 122 241 3.1E-86
PRINTS PR00416 Eukaryotic DNA topoisomerase I signature IPR001631 DNA topoisomerase I 131 150 3.2E-6
SUPERFAMILY SSF55869 IPR035447 DNA topoisomerase I, N-terminal 31 92 3.66E-23
CDD cd00659 Topo_IB_C IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type 95 305 1.06274E-74
Gene3D G3DSA:3.30.66.10 IPR035447 DNA topoisomerase I, N-terminal 13 98 5.2E-33
PRINTS PR00416 Eukaryotic DNA topoisomerase I signature IPR001631 DNA topoisomerase I 175 191 3.2E-6
PRINTS PR00416 Eukaryotic DNA topoisomerase I signature IPR001631 DNA topoisomerase I 154 168 3.2E-6
Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type 91 292 2.7E-32
PRINTS PR00416 Eukaryotic DNA topoisomerase I signature IPR001631 DNA topoisomerase I 240 254 3.2E-6
Gene3D G3DSA:1.10.132.120 99 317 3.1E-86
SUPERFAMILY SSF56349 IPR011010 DNA breaking-rejoining enzyme, catalytic core 87 315 9.12E-72

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.