Burkholderia cenocepacia J2315, BCAM2476 (nadE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00552
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008795 NAD+ synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00193
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004359 glutaminase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00552
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008795 NAD+ synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00193
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009435 NAD biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00552
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00552
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004359 glutaminase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00552
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009435 NAD biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00552
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00552
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00552
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00760 Nicotinate and nicotinamide metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj00760 Nicotinate and nicotinamide metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF02540 NAD synthase IPR022310 NAD/GMP synthase 29 273 2.4E-58
TIGRFAM TIGR00552 nadE: NAD+ synthetase IPR003694 NAD(+) synthetase 28 278 6.9E-61
Gene3D G3DSA:3.40.50.620 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 1 266 1.0E-74
Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. IPR022926 NH(3)-dependent NAD(+) synthetase 24 276 49.932
CDD cd00553 NAD_synthase IPR003694 NAD(+) synthetase 23 270 7.3544E-84
SUPERFAMILY SSF52402 10 279 9.43E-76

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.