Strain |
Burkholderia cenocepacia J2315
GCF_000009485.1|latest |
Locus Tag |
BCAM0859
|
NCBI Locus Tag | QU43_RS58675 |
Name |
bceF
|
Replicon | chromosome 2 |
Genomic location | 947057 - 949282 (+ strand) |
Comment | Member of the bce-I gene cluster |
RefSeq | WP_006482932.1 |
GI | 206562715 |
Entrez | 6930374 |
GI | 206562715 |
INSDC | CAR54717.1 |
NCBI Locus Tag | QU43_RS58675 |
NCBI Old Locus Tag | BCAM0859 |
RefSeq | WP_006482932.1,GeneID |
UniParc | UPI00017B99F2 |
UniProtKB Acc | B4EMX8 |
UniProtKB ID | B4EMX8_BURCJ |
UniRef100 | UniRef100_B4EMX8 |
UniRef50 | UniRef50_A9ANS7 |
UniRef90 | UniRef90_A9ANS7 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
tyrosine autokinase BceF
|
Synonyms |
tyrosine autokinase BceF |
Evidence for Translation | |
Charge (pH 7) | 1.93 |
Kyte-Doolittle Hydrophobicity Value | -0.034 |
Molecular Weight (kDa) | 79575.6 |
Isoelectric Point (pI) | 7.78 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 468 genera
|
Burkholderia Ortholog Group |
BG004851 (638 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BCAM0859
Search term: bceF
Search term: tyrosine autokinase BceF
|
Functional analysis of Burkholderia cepacia genes bceD and bceF, encoding a phosphotyrosine phosphatase and a tyrosine autokinase, respectively: role in exopolysaccharide biosynthesis and biofilm formation.
Ferreira AS, Leitão JH, Sousa SA, Cosme AM, Sá-Correia I, Moreira LM
Appl Environ Microbiol 2007 Jan;73(2):524-34
PubMed ID: 17114319
|
Identification and physical organization of the gene cluster involved in the biosynthesis of Burkholderia cepacia complex exopolysaccharide.
Moreira LM, Videira PA, Sousa SA, Leitão JH, Cunha MV, Sá-Correia I
Biochem Biophys Res Commun 2003 Dec 12;312(2):323-33
PubMed ID: 14637140
|
Comparative transcriptomic analysis of the Burkholderia cepacia tyrosine kinase bceF mutant reveals a role in tolerance to stress, biofilm formation, and virulence.
Ferreira AS, Silva IN, Oliveira VH, Becker JD, Givskov M, Ryan RP, Fernandes F, Moreira LM
Appl Environ Microbiol 2013 May;79(9):3009-20
PubMed ID: 23435894
|
The tyrosine kinase BceF and the phosphotyrosine phosphatase BceD of Burkholderia contaminans are required for efficient invasion and epithelial disruption of a cystic fibrosis lung epithelial cell line.
Ferreira AS, Silva IN, Fernandes F, Pilkington R, Callaghan M, McClean S, Moreira LM
Infect Immun 2015 Feb;83(2):812-21
PubMed ID: 25486990
|
Tyrosine Phosphorylation and Dephosphorylation in Burkholderia cenocepacia Affect Biofilm Formation, Growth under Nutritional Deprivation, and Pathogenicity.
Andrade A, Tavares-Carreón F, Khodai-Kalaki M, Valvano MA
Appl Environ Microbiol 2016 Feb 1;82(3):843-56
PubMed ID: 26590274
|
Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863
|