Burkholderia cenocepacia J2315, BCAL3429

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00317
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00317
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01183
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01183
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc guanosine deoxyribonucleotides <i>de novo</i> biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc guanosine deoxyribonucleotides <i>de novo</i> biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00983 Drug metabolism - other enzymes InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00240 Pyrimidine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleotides biosynthesis from CTP InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00480 Glutathione metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleotides <i>de novo</i> biosynthesis IV InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleotides <i>de novo</i> biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00240 Pyrimidine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleotides <i>de novo</i> biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc adenosine deoxyribonucleotides <i>de novo</i> biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc adenosine deoxyribonucleotides <i>de novo</i> biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00230 Purine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00230 Purine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 451 470 6.6E-44
Gene3D G3DSA:3.20.70.20 230 926 1.1E-245
Pfam PF00317 Ribonucleotide reductase, all-alpha domain IPR013509 Ribonucleotide reductase large subunit, N-terminal 299 372 2.8E-21
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 666 688 6.6E-44
Coils Coil 1002 1003 -
ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. IPR000788 Ribonucleotide reductase large subunit, C-terminal 759 781 -
MobiDBLite mobidb-lite consensus disorder prediction 1 28 -
ProSiteProfiles PS51161 ATP-cone domain profile. IPR005144 ATP-cone domain 158 247 14.937
Pfam PF02867 Ribonucleotide reductase, barrel domain IPR000788 Ribonucleotide reductase large subunit, C-terminal 376 915 1.1E-182
ProSiteProfiles PS51161 ATP-cone domain profile. IPR005144 ATP-cone domain 40 140 19.737
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 770 797 6.6E-44
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 694 717 6.6E-44
Pfam PF03477 ATP cone domain IPR005144 ATP-cone domain 41 137 8.2E-19
MobiDBLite mobidb-lite consensus disorder prediction 1 22 -
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 586 597 6.6E-44
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 628 651 6.6E-44
SUPERFAMILY SSF51998 375 918 3.05E-180
SUPERFAMILY SSF48168 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal 163 374 2.62E-63
CDD cd01679 RNR_I 324 918 0.0
TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit IPR013346 Ribonucleotide reductase, class I , alpha subunit 302 918 1.3E-210

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.