Burkholderia cenocepacia J2315, BCAL3370 (proA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006561 proline biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00412
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00171
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00171
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0050661 NADP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000151
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.309.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004350 glutamate-5-semialdehyde dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00412
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj00332 Carbapenem biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj00330 Arginine and proline metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00332 Carbapenem biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc L-<i>N<sup>&delta;</sup></i>-acetylornithine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc L-proline biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01230 Biosynthesis of amino acids 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00330 Arginine and proline metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01130 Biosynthesis of antibiotics 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.605.10 IPR016162 Aldehyde dehydrogenase, N-terminal 25 431 1.2E-169
Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. IPR000965 GPR domain 18 434 41.362
Pfam PF00171 Aldehyde dehydrogenase family IPR015590 Aldehyde dehydrogenase domain 24 325 6.9E-17
ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site 341 362 -
CDD cd07079 ALDH_F18-19_ProA-GPR IPR000965 GPR domain 20 429 0.0
Coils Coil 42 62 -
TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase IPR000965 GPR domain 26 424 3.8E-149
PIRSF PIRSF000151 IPR012134 Glutamate-5-semialdehyde dehydrogenase 11 435 6.7E-175
Pfam PF00171 Aldehyde dehydrogenase family IPR015590 Aldehyde dehydrogenase domain 327 397 4.4E-8
Gene3D G3DSA:3.40.309.10 IPR016163 Aldehyde dehydrogenase, C-terminal 239 392 1.2E-169
SUPERFAMILY SSF53720 IPR016161 Aldehyde/histidinol dehydrogenase 18 432 5.89E-118

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.