Burkholderia cenocepacia J2315, BCAL3220 (wcbR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00107
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.47.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS01162
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008270 zinc ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS01162
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0031177 phosphopantetheine binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00823
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016740 transferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.366.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00698 Acyl transferase domain IPR014043 Acyl transferase 541 857 2.6E-62
SUPERFAMILY SSF55048 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding 672 738 1.96E-10
SUPERFAMILY SSF53901 IPR016039 Thiolase-like 2 427 6.24E-100
Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain IPR014030 Beta-ketoacyl synthase, N-terminal 3 252 6.1E-90
Gene3D G3DSA:3.90.180.10 1790 2132 4.3E-118
Pfam PF16197 Ketoacyl-synthetase C-terminal extension IPR032821 Ketoacyl-synthetase, C-terminal extension 381 497 9.4E-19
Pfam PF00107 Zinc-binding dehydrogenase IPR013149 Alcohol dehydrogenase, C-terminal 1942 2054 1.5E-23
SMART SM00825 Beta-ketoacyl synthase IPR020841 Polyketide synthase, beta-ketoacyl synthase domain 5 431 3.9E-214
Pfam PF13489 Methyltransferase domain 1383 1548 1.0E-8
Pfam PF14765 Polyketide synthase dehydratase IPR020807 Polyketide synthase, dehydratase domain 910 1190 5.3E-54
Gene3D G3DSA:3.40.366.10 IPR001227 Acyl transferase domain superfamily 539 851 4.1E-122
CDD cd00833 PKS 5 426 0.0
SMART SM00823 Phosphopantetheine attachment site IPR020806 Polyketide synthase, phosphopantetheine-binding domain 2419 2490 1.3E-8
Gene3D G3DSA:3.30.70.3290 455 894 4.1E-122
SUPERFAMILY SSF53335 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase 1383 1553 1.1E-13
SMART SM00826 IPR020807 Polyketide synthase, dehydratase domain 910 1072 2.5E-39
Gene3D G3DSA:3.40.50.720 1575 1789 4.4E-28
Gene3D G3DSA:3.10.129.110 IPR042104 Polyketide synthase, dehydratase domain superfamily 901 1193 1.9E-55
Gene3D G3DSA:3.40.47.10 IPR016039 Thiolase-like 1 454 1.1E-187
SUPERFAMILY SSF52151 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase 537 839 1.23E-61
SUPERFAMILY SSF51735 IPR036291 NAD(P)-binding domain superfamily 1589 1774 4.01E-29
SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. IPR020801 Polyketide synthase, acyl transferase domain 541 848 5.8E-94
SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2138 2319 2.6E-48
Gene3D G3DSA:3.40.50.150 1353 1559 9.6E-14
Gene3D G3DSA:1.10.1200.10 IPR036736 ACP-like superfamily 2404 2496 2.3E-11
ProSiteProfiles PS50075 Carrier protein (CP) domain profile. IPR009081 Phosphopantetheine binding ACP domain 2413 2490 12.807
Gene3D G3DSA:3.40.50.720 2133 2390 5.1E-59
SMART SM01294 2420 2486 0.0017
ProSitePatterns PS00606 Beta-ketoacyl synthases active site. IPR018201 Beta-ketoacyl synthase, active site 165 181 -
Pfam PF00550 Phosphopantetheine attachment site IPR009081 Phosphopantetheine binding ACP domain 2421 2486 9.6E-11
SUPERFAMILY SSF47336 IPR036736 ACP-like superfamily 2418 2507 3.66E-13
Pfam PF08659 KR domain IPR013968 Polyketide synthase, ketoreductase domain 2138 2318 3.0E-60
Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain IPR014031 Beta-ketoacyl synthase, C-terminal 260 378 2.2E-35
ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site 1931 1952 -
SMART SM00829 IPR020843 Polyketide synthase, enoylreductase domain 1798 2113 3.2E-176
SUPERFAMILY SSF50129 IPR011032 GroES-like superfamily 1795 1936 9.75E-28
SUPERFAMILY SSF51735 IPR036291 NAD(P)-binding domain superfamily 2138 2341 2.98E-37
CDD cd05195 enoyl_red 1816 2113 3.32209E-120
SUPERFAMILY SSF51735 IPR036291 NAD(P)-binding domain superfamily 1903 2057 1.42E-48

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.