Burkholderia cenocepacia J2315, BCAL3049 (hemL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0033014 tetrapyrrole biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00713
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0042286 glutamate-1-semialdehyde 2,1-aminomutase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00713
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.640.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0030170 pyridoxal phosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00202
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008483 transaminase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00202
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc tetrapyrrole biosynthesis I (from glutamate) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00860 Porphyrin and chlorophyll metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00860 Porphyrin and chlorophyll metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. IPR005814 Aminotransferase class-III 234 270 -
SUPERFAMILY SSF53383 IPR015424 Pyridoxal phosphate-dependent transferase 2 423 3.09E-126
TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase 5 423 9.0E-187
CDD cd00610 OAT_like IPR005814 Aminotransferase class-III 7 412 1.36054E-117
Gene3D G3DSA:3.90.1150.10 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 7 418 2.0E-172
Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase 3 425 102.318
Gene3D G3DSA:3.40.640.10 IPR015421 Pyridoxal phosphate-dependent transferase, major domain 69 317 2.0E-172
Pfam PF00202 Aminotransferase class-III IPR005814 Aminotransferase class-III 32 395 2.6E-75

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.