Burkholderia cenocepacia J2315, BCAL2978 (fdsA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0009055 | electron transfer activity |
Inferred from Sequence Model
Term mapped from: InterPro:PS00932
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0051536 | iron-sulfur cluster binding |
Inferred from Sequence Model
Term mapped from: InterPro:PS51085
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0055114 | oxidation-reduction process |
Inferred from Sequence Model
Term mapped from: InterPro:PF00384
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0015942 | formate metabolic process |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01591
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0008863 | formate dehydrogenase (NAD+) activity |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01591
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0043546 | molybdopterin cofactor binding |
Inferred from Sequence Model
Term mapped from: InterPro:PF01568
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0016491 | oxidoreductase activity |
Inferred from Sequence Model
Term mapped from: InterPro:PF00384
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| MetaCyc | purine nucleobases degradation II (anaerobic) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG (InterPro) | 00630 | Glyoxylate and dicarboxylate metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| KEGG | bcj01100 | Metabolic pathways | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | oxalate degradation VI | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | bcj01120 | Microbial metabolism in diverse environments | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG (InterPro) | 00680 | Methane metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| MetaCyc | oxalate degradation III | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | bcj00630 | Glyoxylate and dicarboxylate metabolism | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bcj01200 | Carbon metabolism | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bcj00680 | Methane metabolism | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | formate oxidation to CO<sub>2</sub> | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| ProSiteProfiles | PS51379 | 4Fe-4S ferredoxin-type iron-sulfur binding domain profile. | IPR017896 | 4Fe-4S ferredoxin-type, iron-sulphur binding domain | 229 | 258 | 9.02 |
| SUPERFAMILY | SSF54292 | IPR036010 | 2Fe-2S ferredoxin-like superfamily | 48 | 120 | 5.42E-19 | |
| ProSiteProfiles | PS51839 | His(Cys)3-ligated-type [4Fe-4S] domain profile. | IPR019574 | NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding | 124 | 163 | 13.235 |
| SMART | SM00929 | IPR019574 | NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding | 129 | 169 | 5.4E-19 | |
| Gene3D | G3DSA:3.30.70.20 | 174 | 256 | 3.0E-23 | |||
| SUPERFAMILY | SSF53706 | 266 | 794 | 1.96E-190 | |||
| Pfam | PF13510 | 2Fe-2S iron-sulfur cluster binding domain | 46 | 122 | 5.5E-25 | ||
| Gene3D | G3DSA:3.10.20.740 | 48 | 168 | 1.5E-38 | |||
| TIGRFAM | TIGR01591 | Fdh-alpha: formate dehydrogenase, alpha subunit | IPR006478 | Formate dehydrogenase, alpha subunit | 270 | 945 | 6.9E-284 |
| Gene3D | G3DSA:2.40.40.20 | 834 | 948 | 3.5E-36 | |||
| Pfam | PF10588 | NADH-ubiquinone oxidoreductase-G iron-sulfur binding region | IPR019574 | NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding | 129 | 168 | 4.2E-17 |
| Pfam | PF12838 | 4Fe-4S dicluster domain | IPR017896 | 4Fe-4S ferredoxin-type, iron-sulphur binding domain | 194 | 251 | 4.2E-6 |
| SUPERFAMILY | SSF50692 | IPR009010 | Aspartate decarboxylase-like domain superfamily | 805 | 946 | 8.14E-42 | |
| SUPERFAMILY | SSF54862 | 121 | 258 | 1.51E-37 | |||
| ProSiteProfiles | PS51085 | 2Fe-2S ferredoxin-type iron-sulfur binding domain profile. | IPR001041 | 2Fe-2S ferredoxin-type iron-sulfur binding domain | 46 | 124 | 10.605 |
| Gene3D | G3DSA:2.20.25.90 | 266 | 318 | 6.8E-16 | |||
| ProSiteProfiles | PS51669 | Prokaryotic molybdopterin oxidoreductases 4Fe-4S domain profile. | IPR006963 | Molybdopterin oxidoreductase, 4Fe-4S domain | 265 | 321 | 17.959 |
| Gene3D | G3DSA:3.40.50.740 | 327 | 796 | 3.0E-174 | |||
| Pfam | PF00384 | Molybdopterin oxidoreductase | IPR006656 | Molybdopterin oxidoreductase | 322 | 739 | 3.8E-75 |
| ProSitePatterns | PS00932 | Prokaryotic molybdopterin oxidoreductases signature 3. | IPR006655 | Molybdopterin oxidoreductase, prokaryotic, conserved site | 875 | 902 | - |
| CDD | cd00508 | MopB_CT_Fdh-Nap-like | 834 | 947 | 6.82343E-44 | ||
| Pfam | PF04879 | Molybdopterin oxidoreductase Fe4S4 domain | IPR006963 | Molybdopterin oxidoreductase, 4Fe-4S domain | 266 | 317 | 1.0E-14 |
| Gene3D | G3DSA:3.40.228.10 | 402 | 609 | 3.0E-174 | |||
| SMART | SM00926 | IPR006963 | Molybdopterin oxidoreductase, 4Fe-4S domain | 265 | 319 | 1.7E-14 | |
| PIRSF | PIRSF036643 | 43 | 978 | 0.0 | |||
| ProSitePatterns | PS00198 | 4Fe-4S ferredoxin-type iron-sulfur binding region signature. | IPR017900 | 4Fe-4S ferredoxin, iron-sulphur binding, conserved site | 195 | 206 | - |
| ProSiteProfiles | PS51379 | 4Fe-4S ferredoxin-type iron-sulfur binding domain profile. | IPR017896 | 4Fe-4S ferredoxin-type, iron-sulphur binding domain | 186 | 217 | 7.937 |
| Pfam | PF01568 | Molydopterin dinucleotide binding domain | IPR006657 | Molybdopterin dinucleotide-binding domain | 837 | 941 | 3.8E-29 |
| CDD | cd00207 | fer2 | IPR001041 | 2Fe-2S ferredoxin-type iron-sulfur binding domain | 48 | 119 | 7.0223E-9 |
| CDD | cd02753 | MopB_Formate-Dh-H | IPR041924 | Formate dehydrogenase H, N-terminal | 270 | 826 | 0.0 |
| ProSitePatterns | PS00198 | 4Fe-4S ferredoxin-type iron-sulfur binding region signature. | IPR017900 | 4Fe-4S ferredoxin, iron-sulphur binding, conserved site | 238 | 249 | - |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.