Burkholderia cenocepacia J2315, BCAL2908 (fumC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0045239 tricarboxylic acid cycle enzyme complex
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01362
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006106 fumarate metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01362
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00163
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016829 lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF10415
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006099 tricarboxylic acid cycle
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF10415
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004333 fumarate hydratase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01362
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00720 Carbon fixation pathways in prokaryotes InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj01120 Microbial metabolism in diverse environments 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc methylaspartate cycle InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01200 Carbon metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00020 Citrate cycle (TCA cycle) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01130 Biosynthesis of antibiotics 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj00620 Pyruvate metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc reductive TCA cycle II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc partial TCA cycle (obligate autotrophs) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc TCA cycle II (plants and fungi) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00620 Pyruvate metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc superpathway of glyoxylate cycle and fatty acid degradation InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc TCA cycle VII (acetate-producers) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00020 Citrate cycle (TCA cycle) 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc anaerobic energy metabolism (invertebrates, mitochondrial) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 318 334 4.0E-35
Gene3D G3DSA:1.20.200.10 140 408 8.6E-122
ProSitePatterns PS00163 Fumarate lyases signature. IPR020557 Fumarate lyase, conserved site 318 327 -
PRINTS PR00145 Argininosuccinate lyase family signature 318 334 4.3E-5
Pfam PF00206 Lyase IPR022761 Fumarate lyase, N-terminal 13 343 4.0E-119
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 181 199 4.0E-35
Hamap MF_00743 Fumarate hydratase class II [fumC]. IPR005677 Fumarate hydratase, class II 5 463 91.407
CDD cd01362 Fumarase_classII IPR005677 Fumarate hydratase, class II 6 460 0.0
Gene3D G3DSA:1.10.275.10 IPR024083 Fumarase/histidase, N-terminal 6 139 8.6E-57
Gene3D G3DSA:1.10.40.30 409 464 1.3E-31
SUPERFAMILY SSF48557 IPR008948 L-Aspartase-like 5 460 3.53E-155
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 272 299 4.0E-35
TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II IPR005677 Fumarate hydratase, class II 5 462 6.9E-238
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 135 153 4.0E-35
PRINTS PR00145 Argininosuccinate lyase family signature 176 196 4.3E-5
Pfam PF10415 Fumarase C C-terminus IPR018951 Fumarase C, C-terminal 409 462 4.2E-26

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.