Burkholderia cenocepacia J2315, BCAL2409 (dnaE)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0009244	lipopolysaccharide core region biosynthetic process	IGC Inferred from Genomic Context	ECO:0000317 genomic context evidence used in manual assertion	19525227	Reviewed by curator
Biological Process	GO:0009244	lipopolysaccharide core region biosynthetic process	IGC Inferred from Genomic Context	ECO:0000177 genomic context evidence
Molecular Function	GO:0003824	catalytic activity	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF89550	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0008408	3'-5' exonuclease activity	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00594	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006260	DNA replication	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00594	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0003676	nucleic acid binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF01336	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	bcj01100	Metabolic pathways	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj03440	Homologous recombination	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj03430	Mismatch repair	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj00230	Purine metabolism	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj00240	Pyrimidine metabolism	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj03030	DNA replication	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Pfam	PF17657	Bacterial DNA polymerase III alpha subunit finger domain	IPR040982	DNA polymerase III alpha subunit finger domain	565	730	2.9E-64
Pfam	PF01336	OB-fold nucleic acid binding domain	IPR004365	OB-fold nucleic acid binding domain, AA-tRNA synthetase-type	988	1048	2.3E-6
CDD	cd04485	DnaE_OBF			987	1071	1.2002E-21
Coils	Coil				1177	1177	-
MobiDBLite	mobidb-lite	consensus disorder prediction			1099	1121	-
Pfam	PF02811	PHP domain	IPR004013	PHP domain	8	173	4.4E-43
Pfam	PF07733	Bacterial DNA polymerase III alpha NTPase domain	IPR011708	Bacterial DNA polymerase III, alpha subunit, NTPase domain	293	562	6.8E-105
Gene3D	G3DSA:1.10.10.1600		IPR041931	Bacterial DNA polymerase III alpha subunit, thumb domain	435	514	1.3E-27
Gene3D	G3DSA:3.20.20.140				1	270	4.1E-86
CDD	cd07433	PHP_PolIIIA_DnaE1			5	282	2.16319E-149
Pfam	PF14579	Helix-hairpin-helix motif	IPR029460	DNA polymerase, helix-hairpin-helix motif	804	898	1.6E-28
SMART	SM00481		IPR003141	Polymerase/histidinol phosphatase, N-terminal	7	74	2.8E-24
SUPERFAMILY	SSF89550		IPR016195	Polymerase/histidinol phosphatase-like	6	264	1.57E-11
Gene3D	G3DSA:2.40.50.140				971	1069	1.9E-9
TIGRFAM	TIGR00594	polc: DNA polymerase III, alpha subunit	IPR004805	DNA polymerase III, alpha subunit	6	1022	0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.