Burkholderia cenocepacia J2315, BCAL2208 (pdhB)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0004742 | dihydrolipoyllysine-residue acetyltransferase activity |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0006096 | glycolytic process |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Cellular Component | GO:0045254 | pyruvate dehydrogenase complex |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0016746 | transferase activity, transferring acyl groups |
Inferred from Sequence Model
Term mapped from: InterPro:SSF47005
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG | bcj01200 | Carbon metabolism | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bcj01130 | Biosynthesis of antibiotics | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG (InterPro) | 00010 | Glycolysis / Gluconeogenesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| KEGG (InterPro) | 00020 | Citrate cycle (TCA cycle) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| KEGG | bcj01110 | Biosynthesis of secondary metabolites | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bcj00010 | Glycolysis / Gluconeogenesis | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bcj01100 | Metabolic pathways | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bcj00620 | Pyruvate metabolism | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG (InterPro) | 00620 | Pyruvate metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| KEGG | bcj01120 | Microbial metabolism in diverse environments | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bcj00020 | Citrate cycle (TCA cycle) | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Pfam | PF02817 | e3 binding domain | IPR004167 | Peripheral subunit-binding domain | 245 | 278 | 1.4E-16 |
| Pfam | PF00364 | Biotin-requiring enzyme | IPR000089 | Biotin/lipoyl attachment | 118 | 188 | 1.2E-21 |
| ProSiteProfiles | PS51826 | Peripheral subunit-binding (PSBD) domain profile. | IPR004167 | Peripheral subunit-binding domain | 245 | 282 | 21.378 |
| ProSiteProfiles | PS50968 | Biotinyl/lipoyl domain profile. | IPR000089 | Biotin/lipoyl attachment | 4 | 78 | 27.395 |
| SUPERFAMILY | SSF51230 | IPR011053 | Single hybrid motif | 116 | 209 | 2.22E-24 | |
| Gene3D | G3DSA:4.10.320.10 | IPR036625 | E3-binding domain superfamily | 231 | 285 | 4.5E-19 | |
| CDD | cd06849 | lipoyl_domain | 5 | 77 | 2.50009E-20 | ||
| ProSitePatterns | PS00189 | 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. | IPR003016 | 2-oxo acid dehydrogenase, lipoyl-binding site | 140 | 169 | - |
| SUPERFAMILY | SSF52777 | 309 | 547 | 4.14E-85 | |||
| Gene3D | G3DSA:2.40.50.100 | 116 | 194 | 7.1E-22 | |||
| CDD | cd06849 | lipoyl_domain | 118 | 189 | 1.19019E-20 | ||
| Pfam | PF00198 | 2-oxoacid dehydrogenases acyltransferase (catalytic domain) | IPR001078 | 2-oxoacid dehydrogenase acyltransferase, catalytic domain | 322 | 546 | 5.4E-80 |
| TIGRFAM | TIGR01348 | PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase | IPR006256 | Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex | 96 | 547 | 1.7E-197 |
| ProSiteProfiles | PS50968 | Biotinyl/lipoyl domain profile. | IPR000089 | Biotin/lipoyl attachment | 116 | 190 | 27.446 |
| Gene3D | G3DSA:3.30.559.10 | IPR023213 | Chloramphenicol acetyltransferase-like domain superfamily | 305 | 547 | 3.9E-94 | |
| ProSitePatterns | PS00189 | 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. | IPR003016 | 2-oxo acid dehydrogenase, lipoyl-binding site | 28 | 57 | - |
| Pfam | PF00364 | Biotin-requiring enzyme | IPR000089 | Biotin/lipoyl attachment | 6 | 76 | 6.0E-20 |
| SUPERFAMILY | SSF51230 | IPR011053 | Single hybrid motif | 3 | 96 | 1.44E-23 | |
| Gene3D | G3DSA:2.40.50.100 | 4 | 80 | 1.3E-20 | |||
| SUPERFAMILY | SSF47005 | IPR036625 | E3-binding domain superfamily | 242 | 283 | 6.93E-13 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.