Burkholderia cenocepacia J2315, BCAL2198 (iscS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.640.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0030170 pyridoxal phosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02006
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0044571 [2Fe-2S] cluster assembly
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02006
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0031071 cysteine desulfurase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02006
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj00730 Thiamine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc [2Fe-2S] iron-sulfur cluster biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00730 Thiamine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj04122 Sulfur relay system 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.640.10 IPR015421 Pyridoxal phosphate-dependent transferase, major domain 21 265 1.9E-165
SUPERFAMILY SSF53383 IPR015424 Pyridoxal phosphate-dependent transferase 10 394 1.45E-113
ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site 200 219 -
Hamap MF_00331 Cysteine desulfurase IscS [iscS]. IPR010240 Cysteine desulfurase IscS 6 398 55.289
Pfam PF00266 Aminotransferase class-V IPR000192 Aminotransferase class V domain 10 370 4.9E-89
Coils Coil 259 279 -
Gene3D G3DSA:3.90.1150.10 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 10 377 1.9E-165
PIRSF PIRSF005572 IPR016454 Cysteine desulfurase 7 387 5.0E-136
TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS IPR010240 Cysteine desulfurase IscS 7 407 3.6E-231

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.