Burkholderia cenocepacia J2315, BCAL0732 (gshB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004363 glutathione synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02955
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0046872 metal ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS50975
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.30.1490.20
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006750 glutathione biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02955
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00270 Cysteine and methionine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc ophthalmate biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00480 Glutathione metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj00480 Glutathione metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.50.20 6 118 9.5E-101
Hamap MF_00162 Glutathione synthetase [gshB]. IPR006284 Glutathione synthetase, prokaryotic 1 318 161.167
Gene3D G3DSA:3.30.1490.20 IPR013815 ATP-grasp fold, subdomain 1 141 205 9.5E-101
Gene3D G3DSA:3.30.470.20 119 298 9.5E-101
SUPERFAMILY SSF52440 IPR016185 Pre-ATP-grasp domain superfamily 1 126 4.89E-38
ProSiteProfiles PS50975 ATP-grasp fold profile. IPR011761 ATP-grasp fold 129 314 25.003
TIGRFAM TIGR01380 glut_syn: glutathione synthase IPR006284 Glutathione synthetase, prokaryotic 1 316 3.2E-121
Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain IPR004218 Prokaryotic glutathione synthetase, ATP-binding 128 301 3.5E-72
SUPERFAMILY SSF56059 128 315 1.43E-57
Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain IPR004215 Prokaryotic glutathione synthetase, N-terminal 1 124 2.5E-40

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.