Burkholderia cenocepacia J2315, BCAL0664 (bioB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.20.20.70
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051536 iron-sulfur cluster binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00729
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009102 biotin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00433
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004076 biotin synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00433
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc biotin biosynthesis from 8-amino-7-oxononanoate II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00780 Biotin metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00780 Biotin metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd01335 Radical_SAM 67 259 1.07557E-15
SMART SM00876 IPR010722 Biotin and thiamin synthesis-associated domain 237 329 1.6E-46
SFLD SFLDS00029 Radical SAM IPR007197 Radical SAM 19 334 0.0
SUPERFAMILY SSF102114 22 328 2.49E-92
Pfam PF06968 Biotin and Thiamin Synthesis associated domain IPR010722 Biotin and thiamin synthesis-associated domain 237 327 1.6E-18
Hamap MF_01694 Biotin synthase [bioB]. IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB 22 330 42.552
Pfam PF04055 Radical SAM superfamily IPR007197 Radical SAM 67 219 2.4E-16
SMART SM00729 IPR006638 Elp3/MiaB/NifB 60 272 2.6E-39
Gene3D G3DSA:3.20.20.70 IPR013785 Aldolase-type TIM barrel 22 332 2.6E-128
PIRSF PIRSF001619 IPR024177 Biotin synthase 6 336 4.7E-136
TIGRFAM TIGR00433 bioB: biotin synthase IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB 32 327 1.7E-125
SFLD SFLDF00272 biotin synthase IPR024177 Biotin synthase 19 334 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.