Burkholderia cenocepacia J2315, BCAL0439

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006750 glutathione biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00578
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF55931
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004357 glutamate-cysteine ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00578
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj00480 Glutathione metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00270 Cysteine and methionine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc ergothioneine biosynthesis I (bacteria) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc ophthalmate biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc homoglutathione biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00480 Glutathione metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF04262 Glutamate-cysteine ligase IPR007370 Glutamate--cysteine ligase 14 385 1.6E-160
TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase IPR006334 Glutamate--cysteine ligase, monofunctional 23 523 2.8E-187
Gene3D G3DSA:3.30.590.20 24 529 3.2E-185
SUPERFAMILY SSF55931 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain 14 520 4.97E-187
Hamap MF_00578 Glutamate--cysteine ligase [gshA]. IPR006334 Glutamate--cysteine ligase, monofunctional 1 533 221.853

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.