Burkholderia cenocepacia J2315, BCAL0318 (hisF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000107 imidazoleglycerol-phosphate synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01013
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000105 histidine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01013
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.20.20.70
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj01230 Biosynthesis of amino acids 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00340 Histidine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj00340 Histidine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00977 Histidine biosynthesis protein IPR006062 Histidine biosynthesis 6 239 1.4E-90
Gene3D G3DSA:3.20.20.70 IPR013785 Aldolase-type TIM barrel 1 257 3.8E-111
CDD cd04731 HisF IPR004651 Histidine biosynthesis, HisF 5 251 2.77679E-149
Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. IPR004651 Histidine biosynthesis, HisF 2 256 49.333
SUPERFAMILY SSF51366 IPR011060 Ribulose-phosphate binding barrel 3 256 5.73E-84
TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit IPR004651 Histidine biosynthesis, HisF 3 256 7.5E-115

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.