Burkholderia cenocepacia J2315, BCAL0314 (hisB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004424 imidazoleglycerol-phosphate dehydratase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00954
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000105 histidine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00954
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj01230 Biosynthesis of amino acids 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj00340 Histidine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site 61 74 -
CDD cd07914 IGPD IPR000807 Imidazoleglycerol-phosphate dehydratase 4 195 1.72063E-117
SUPERFAMILY SSF54211 IPR020568 Ribosomal protein S5 domain 2-type fold 88 178 1.52E-33
Pfam PF00475 Imidazoleglycerol-phosphate dehydratase IPR000807 Imidazoleglycerol-phosphate dehydratase 31 174 7.6E-63
SUPERFAMILY SSF54211 IPR020568 Ribosomal protein S5 domain 2-type fold 1 86 1.39E-33
Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. IPR000807 Imidazoleglycerol-phosphate dehydratase 2 195 43.128
Gene3D G3DSA:3.30.230.40 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily 90 195 6.7E-38
ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site 156 168 -
Gene3D G3DSA:3.30.230.40 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily 1 89 6.9E-37

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.