Burkholderia cenocepacia J2315, BCAL0312 (hisD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0000105 histidine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00069
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00069
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00069
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008270 zinc ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00069
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004399 histidinol dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00069
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53720
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj00340 Histidine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj01230 Biosynthesis of amino acids 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00340 Histidine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00083 Histidinol dehydrogenase signature IPR012131 Histidinol dehydrogenase 370 388 5.4E-81
TIGRFAM TIGR00069 hisD: histidinol dehydrogenase IPR012131 Histidinol dehydrogenase 37 435 6.6E-157
PRINTS PR00083 Histidinol dehydrogenase signature IPR012131 Histidinol dehydrogenase 179 205 5.4E-81
PRINTS PR00083 Histidinol dehydrogenase signature IPR012131 Histidinol dehydrogenase 260 279 5.4E-81
SUPERFAMILY SSF53720 IPR016161 Aldehyde/histidinol dehydrogenase 30 436 1.18E-83
Gene3D G3DSA:3.40.50.1980 242 358 1.2E-124
PRINTS PR00083 Histidinol dehydrogenase signature IPR012131 Histidinol dehydrogenase 145 171 5.4E-81
Pfam PF00815 Histidinol dehydrogenase IPR012131 Histidinol dehydrogenase 28 436 6.2E-167
PRINTS PR00083 Histidinol dehydrogenase signature IPR012131 Histidinol dehydrogenase 238 259 5.4E-81
PIRSF PIRSF000099 IPR022695 Histidinol dehydrogenase, monofunctional 3 438 9.1E-157
CDD cd06572 Histidinol_dh IPR012131 Histidinol dehydrogenase 33 428 0.0
PRINTS PR00083 Histidinol dehydrogenase signature IPR012131 Histidinol dehydrogenase 209 234 5.4E-81
Hamap MF_01024 Histidinol dehydrogenase [hisD]. IPR012131 Histidinol dehydrogenase 6 436 41.215
PRINTS PR00083 Histidinol dehydrogenase signature IPR012131 Histidinol dehydrogenase 329 354 5.4E-81
Gene3D G3DSA:3.40.50.1980 34 240 1.2E-124
ProSitePatterns PS00611 Histidinol dehydrogenase signature. IPR001692 Histidinol dehydrogenase, conserved site 238 270 -
PRINTS PR00083 Histidinol dehydrogenase signature IPR012131 Histidinol dehydrogenase 37 61 5.4E-81

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.