Burkholderia cenocepacia J2315, BCAL0260 (rpoA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006351 transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.30.1360.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03118
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003899 DNA-directed 5'-3' RNA polymerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03118
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0046983 protein dimerization activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.30.1360.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj00240 Pyrimidine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj00230 Purine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj03020 RNA polymerase 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Coils Coil 323 325 -
SMART SM00662 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type 20 230 1.2E-92
SUPERFAMILY SSF56553 IPR036643 DNA-directed RNA polymerase, insert domain superfamily 50 174 3.79E-41
TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit IPR011773 DNA-directed RNA polymerase, alpha subunit 21 313 9.3E-106
Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type 26 224 5.4E-22
Gene3D G3DSA:3.30.1360.10 IPR036603 RNA polymerase, RBP11-like subunit 14 223 1.2E-80
Gene3D G3DSA:2.170.120.12 IPR036643 DNA-directed RNA polymerase, insert domain superfamily 50 173 1.2E-80
Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain IPR011262 DNA-directed RNA polymerase, insert domain 61 150 2.8E-23
Gene3D G3DSA:1.10.150.20 242 325 1.6E-37
Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain IPR011260 RNA polymerase, alpha subunit, C-terminal 248 305 9.3E-25
CDD cd06928 RNAP_alpha_NTD 13 227 1.8324E-106
Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. IPR011773 DNA-directed RNA polymerase, alpha subunit 2 314 35.105
SUPERFAMILY SSF55257 IPR036603 RNA polymerase, RBP11-like subunit 5 228 3.83E-31
SUPERFAMILY SSF47789 248 320 5.23E-27

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.