Burkholderia dolosa AU0158, AK34_RS17815 (fixL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:P10955
 ECO:0000250
sequence similarity evidence used in manual assertion		 28046077 Reviewed by curator
Biological Process GO:0000160 phosphorelay signal transduction system
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:P10955
 ECO:0000250
sequence similarity evidence used in manual assertion		 28046077 Reviewed by curator
Biological Process GO:0036294 cellular response to decreased oxygen levels
IGI
Inferred from Genetic Interaction
Term mapped from: locus_tag:AK34_RS17810
 ECO:0000054
double mutant phenotype evidence		 28046077 Reviewed by curator
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00512
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00989
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00512
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.30.565.10 IPR036890 Histidine kinase/HSP90-like ATPase superfamily 657 819 9.6E-36
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 801 814 5.1E-13
ProSiteProfiles PS50113 PAC domain profile. IPR000700 PAS-associated, C-terminal 393 445 14.681
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 589 655 3.0E-7
SMART SM00091 IPR000014 PAS domain 319 387 3.0E-7
Gene3D G3DSA:3.30.450.20 446 580 1.8E-7
Gene3D G3DSA:1.10.287.130 593 655 7.3E-18
SMART SM00086 IPR001610 PAC motif 394 436 1.8E-6
CDD cd16920 HATPase_TmoS-FixL-DctS-like 705 814 2.72777E-39
Gene3D G3DSA:3.30.450.20 317 445 1.1E-25
SMART SM00387 IPR003594 Histidine kinase/HSP90-like ATPase 700 817 3.6E-28
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 761 771 5.1E-13
SMART SM00388 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 588 658 2.9E-8
SUPERFAMILY SSF55785 IPR035965 PAS domain superfamily 307 434 1.61E-24
SMART SM00091 IPR000014 PAS domain 448 518 64.0
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 772 790 5.1E-13
ProSiteProfiles PS50109 Histidine kinase domain profile. IPR005467 Histidine kinase domain 595 817 37.865
Pfam PF13188 PAS domain IPR000014 PAS domain 448 492 0.013
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 586 654 4.1717E-7
SUPERFAMILY SSF55785 IPR035965 PAS domain superfamily 433 564 4.36E-9
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 702 814 9.5E-15
CDD cd00130 PAS IPR000014 PAS domain 332 433 9.54817E-15
SUPERFAMILY SSF55874 IPR036890 Histidine kinase/HSP90-like ATPase superfamily 650 815 1.96E-34
TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein IPR000014 PAS domain 318 443 1.6E-24
ProSiteProfiles PS50112 PAS repeat profile. IPR000014 PAS domain 317 389 15.35
Pfam PF00989 PAS fold IPR013767 PAS fold 322 433 1.5E-15
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 743 757 5.1E-13
SUPERFAMILY SSF47384 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 582 656 3.34E-8

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.