Burkholderia thailandensis E264 ATCC 700388, BTH_II2094 (malG)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0009082	branched-chain amino acid biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:PF01450	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0004455	ketol-acid reductoisomerase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF01450	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0055114	oxidation-reduction process	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF48179	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	bte01130	Biosynthesis of antibiotics	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
MetaCyc		L-isoleucine biosynthesis III	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
MetaCyc		pyruvate fermentation to isobutanol (engineered)	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
KEGG (InterPro)	00770	Pantothenate and CoA biosynthesis	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
KEGG (InterPro)	00290	Valine, leucine and isoleucine biosynthesis	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
KEGG	bte00290	Valine, leucine and isoleucine biosynthesis	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG (InterPro)	00270	Cysteine and methionine metabolism	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
KEGG	bte01230	Biosynthesis of amino acids	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bte01100	Metabolic pathways	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bte00770	Pantothenate and CoA biosynthesis	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bte01110	Biosynthesis of secondary metabolites	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
MetaCyc		<i>S</i>-adenosyl-L-methionine cycle II	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
KEGG	bte01210	2-Oxocarboxylic acid metabolism	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
SUPERFAMILY	SSF48179		IPR008927	6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily	184	327	9.86E-16
Pfam	PF07991	Acetohydroxy acid isomeroreductase, NADPH-binding domain	IPR013116	Ketol-acid reductoisomerase, N-terminal	16	178	1.1E-46
Pfam	PF01450	Acetohydroxy acid isomeroreductase, catalytic domain	IPR000506	Ketol-acid reductoisomerase, C-terminal	185	327	4.4E-23
Gene3D	G3DSA:1.10.3730.40				183	335	1.6E-28
SMART	SM00997		IPR015878	S-adenosyl-L-homocysteine hydrolase, NAD binding domain	10	146	0.001
ProSiteProfiles	PS51851	KARI C-terminal domain profile.	IPR000506	Ketol-acid reductoisomerase, C-terminal	183	330	10.517
ProSiteProfiles	PS51850	KARI N-terminal domain profile.	IPR013116	Ketol-acid reductoisomerase, N-terminal	1	182	40.501
SUPERFAMILY	SSF51735		IPR036291	NAD(P)-binding domain superfamily	5	180	4.23E-49
Gene3D	G3DSA:3.40.50.720				4	182	2.4E-57

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.