Burkholderia pseudomallei K96243, BPSS1514 (bopB)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0003934 | GTP cyclohydrolase I activity |
Inferred from Sequence Model
Term mapped from: InterPro:MF_00223
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0046654 | tetrahydrofolate biosynthetic process |
Inferred from Sequence Model
Term mapped from: InterPro:MF_00223
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| MetaCyc | 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | drosopterin and aurodrosopterin biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | <i>erythro</i>-tetrahydrobiopterin biosynthesis II | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | <i>threo</i>-tetrahydrobiopterin biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG (InterPro) | 00790 | Folate biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| MetaCyc | 6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | preQ<sub>0</sub> biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | bps01100 | Metabolic pathways | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bps00790 | Folate biosynthesis | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | erythro-tetrahydrobiopterin biosynthesis I | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| ProSitePatterns | PS00859 | GTP cyclohydrolase I signature 1. | IPR018234 | GTP cyclohydrolase I, conserved site | 88 | 104 | - |
| SUPERFAMILY | SSF55620 | 22 | 209 | 1.04E-56 | |||
| Pfam | PF01227 | GTP cyclohydrolase I | IPR020602 | GTP cyclohydrolase I domain | 32 | 208 | 9.5E-50 |
| Gene3D | G3DSA:3.30.1130.10 | 79 | 210 | 8.6E-36 | |||
| Hamap | MF_00223 | GTP cyclohydrolase 1 [folE]. | IPR001474 | GTP cyclohydrolase I | 27 | 209 | 28.996 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.