Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
---|---|---|---|---|---|---|
Molecular Function | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen |
Inferred from Sequence Model
Term mapped from: InterPro:PR00372
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
Biological Process | GO:0009072 | aromatic amino acid family metabolic process |
Inferred from Sequence Model
Term mapped from: InterPro:PS00367
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
Biological Process | GO:0006559 | L-phenylalanine catabolic process |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01267
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
Biological Process | GO:0055114 | oxidation-reduction process |
Inferred from Sequence Model
Term mapped from: InterPro:PS00367
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
Molecular Function | GO:0005506 | iron ion binding |
Inferred from Sequence Model
Term mapped from: InterPro:PS00367
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
Molecular Function | GO:0004497 | monooxygenase activity |
Inferred from Sequence Model
Term mapped from: InterPro:PS00367
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
Molecular Function | GO:0004505 | phenylalanine 4-monooxygenase activity |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01267
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Database | Xref | Pathway | Version | Evidence | PMID |
---|---|---|---|---|---|
KEGG | bps01230 | Biosynthesis of amino acids | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
KEGG | bps00400 | Phenylalanine, tyrosine and tryptophan biosynthesis | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
KEGG | bps01100 | Metabolic pathways | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
KEGG (InterPro) | 00360 | Phenylalanine metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
KEGG (InterPro) | 00790 | Folate biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
MetaCyc | L-tyrosine biosynthesis IV | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
MetaCyc | L-phenylalanine degradation V | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
KEGG | bps00360 | Phenylalanine metabolism | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
KEGG (InterPro) | 00400 | Phenylalanine, tyrosine and tryptophan biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
---|---|---|---|---|---|---|---|
CDD | cd03348 | pro_PheOH | IPR005960 | Phenylalanine-4-hydroxylase, monomeric form | 22 | 251 | 8.20308E-130 |
ProSitePatterns | PS00367 | Biopterin-dependent aromatic amino acid hydroxylases signature. | IPR018301 | Aromatic amino acid hydroxylase, iron/copper binding site | 130 | 141 | - |
Gene3D | G3DSA:1.10.800.10 | IPR036951 | Aromatic amino acid hydroxylase superfamily | 2 | 297 | 2.4E-106 | |
Pfam | PF00351 | Biopterin-dependent aromatic amino acid hydroxylase | IPR019774 | Aromatic amino acid hydroxylase, C-terminal | 28 | 249 | 2.0E-44 |
PRINTS | PR00372 | Biopterin-dependent aromatic amino acid hydroxylase signature | IPR019774 | Aromatic amino acid hydroxylase, C-terminal | 196 | 214 | 2.8E-10 |
PRINTS | PR00372 | Biopterin-dependent aromatic amino acid hydroxylase signature | IPR019774 | Aromatic amino acid hydroxylase, C-terminal | 228 | 247 | 2.8E-10 |
PRINTS | PR00372 | Biopterin-dependent aromatic amino acid hydroxylase signature | IPR019774 | Aromatic amino acid hydroxylase, C-terminal | 87 | 109 | 2.8E-10 |
ProSiteProfiles | PS51410 | Biopterin-dependent aromatic amino acid hydroxylase family profile. | IPR019774 | Aromatic amino acid hydroxylase, C-terminal | 1 | 297 | 105.093 |
TIGRFAM | TIGR01267 | Phe4hydrox_mono: phenylalanine-4-hydroxylase | IPR005960 | Phenylalanine-4-hydroxylase, monomeric form | 22 | 271 | 8.2E-111 |
SUPERFAMILY | SSF56534 | IPR036329 | Aromatic amino acid monoxygenase, C-terminal domain superfamily | 9 | 291 | 8.37E-104 |