Burkholderia pseudomallei K96243, BPSL3243 (pyrE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006221 pyrimidine nucleotide biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01208
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004588 orotate phosphoribosyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01208
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009116 nucleoside metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00156
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc UMP biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc UMP biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00240 Pyrimidine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00983 Drug metabolism - other enzymes InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00240 Pyrimidine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc UMP biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00156 Phosphoribosyl transferase domain IPR000836 Phosphoribosyltransferase domain 65 160 5.7E-11
TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase IPR004467 Orotate phosphoribosyl transferase domain 15 184 4.8E-32
Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. IPR023031 Orotate phosphoribosyltransferase 1 228 28.092
SUPERFAMILY SSF53271 IPR029057 Phosphoribosyltransferase-like 15 220 2.07E-43
CDD cd06223 PRTases_typeI IPR000836 Phosphoribosyltransferase domain 60 184 1.93522E-16
Gene3D G3DSA:3.40.50.2020 1 228 8.6E-70

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.