Burkholderia pseudomallei K96243, BPSL2904 (tyrZ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006437 tyrosyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00234
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00178
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006418 tRNA aminoacylation for protein translation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00178
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00178
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00234
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004831 tyrosine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00234
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00178
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003723 RNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01479
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00970 Aminoacyl-tRNA biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00970 Aminoacyl-tRNA biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF52374 22 329 5.01E-90
Pfam PF00579 tRNA synthetases class I (W and Y) IPR002305 Aminoacyl-tRNA synthetase, class Ic 49 330 6.8E-74
Gene3D G3DSA:3.10.290.10 IPR036986 RNA-binding S4 domain superfamily 343 411 9.2E-19
PRINTS PR01040 Tyrosyl-tRNA synthetase signature IPR002307 Tyrosine-tRNA ligase 195 217 4.5E-26
Gene3D G3DSA:1.10.240.10 236 342 3.7E-31
Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 15 411 47.208
PRINTS PR01040 Tyrosyl-tRNA synthetase signature IPR002307 Tyrosine-tRNA ligase 178 193 4.5E-26
SUPERFAMILY SSF55174 333 408 7.33E-18
Gene3D G3DSA:3.40.50.620 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 16 235 6.0E-71
CDD cd00165 S4 IPR002942 RNA-binding S4 domain 355 404 7.76918E-8
PRINTS PR01040 Tyrosyl-tRNA synthetase signature IPR002307 Tyrosine-tRNA ligase 228 240 4.5E-26
PRINTS PR01040 Tyrosyl-tRNA synthetase signature IPR002307 Tyrosine-tRNA ligase 63 85 4.5E-26
ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site 59 69 -
ProSiteProfiles PS50889 S4 RNA-binding domain profile. IPR002942 RNA-binding S4 domain 351 411 12.154
TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase IPR002307 Tyrosine-tRNA ligase 20 410 6.1E-120
CDD cd00805 TyrRS_core IPR002307 Tyrosine-tRNA ligase 51 315 3.2773E-109
Pfam PF01479 S4 domain IPR002942 RNA-binding S4 domain 356 397 4.9E-7
SMART SM00363 IPR002942 RNA-binding S4 domain 351 412 7.0E-5

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.