Burkholderia pseudomallei K96243, BPSL2300 (pdhB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016746 transferase activity, transferring acyl groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02817
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006096 glycolytic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006096 glycolytic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004742 dihydrolipoyllysine-residue acetyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004742 dihydrolipoyllysine-residue acetyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0045254 pyruvate dehydrogenase complex
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016746 transferase activity, transferring acyl groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02817
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0045254 pyruvate dehydrogenase complex
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bps00020 Citrate cycle (TCA cycle) 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00020 Citrate cycle (TCA cycle) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00010 Glycolysis / Gluconeogenesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00620 Pyruvate metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01200 Carbon metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00620 Pyruvate metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01120 Microbial metabolism in diverse environments 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00010 Glycolysis / Gluconeogenesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01130 Biosynthesis of antibiotics 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site 141 170 -
SUPERFAMILY SSF51230 IPR011053 Single hybrid motif 117 210 1.44E-24
Gene3D G3DSA:2.40.50.100 4 81 2.7E-21
Pfam PF00364 Biotin-requiring enzyme IPR000089 Biotin/lipoyl attachment 119 190 7.0E-21
TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex 101 546 4.5E-196
SUPERFAMILY SSF51230 IPR011053 Single hybrid motif 3 94 2.62E-23
Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain 321 545 2.5E-81
ProSiteProfiles PS50968 Biotinyl/lipoyl domain profile. IPR000089 Biotin/lipoyl attachment 117 191 28.535
CDD cd06849 lipoyl_domain 5 77 7.42954E-21
CDD cd06849 lipoyl_domain 118 190 8.19204E-21
MobiDBLite mobidb-lite consensus disorder prediction 207 229 -
ProSiteProfiles PS51826 Peripheral subunit-binding (PSBD) domain profile. IPR004167 Peripheral subunit-binding domain 244 281 20.881
ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site 28 57 -
SUPERFAMILY SSF52777 308 546 2.31E-86
MobiDBLite mobidb-lite consensus disorder prediction 207 242 -
SUPERFAMILY SSF47005 IPR036625 E3-binding domain superfamily 241 282 5.75E-12
ProSiteProfiles PS50968 Biotinyl/lipoyl domain profile. IPR000089 Biotin/lipoyl attachment 4 78 28.098
Gene3D G3DSA:3.30.559.10 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily 304 546 1.8E-95
Pfam PF02817 e3 binding domain IPR004167 Peripheral subunit-binding domain 244 277 1.2E-14
Gene3D G3DSA:4.10.320.10 IPR036625 E3-binding domain superfamily 231 284 3.6E-18
Gene3D G3DSA:2.40.50.100 118 196 7.0E-21
Pfam PF00364 Biotin-requiring enzyme IPR000089 Biotin/lipoyl attachment 6 76 1.2E-21

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.