Burkholderia pseudomallei K96243, BPSL1351 (carB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0046872 metal ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS50975
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00866
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006807 nitrogen compound metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01369
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc L-arginine biosynthesis IV (archaebacteria) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00240 Pyrimidine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc UMP biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00250 Alanine, aspartate and glutamate metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc UMP biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00250 Alanine, aspartate and glutamate metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00240 Pyrimidine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc L-arginine biosynthesis III (via <i>N</i>-acetyl-L-citrulline) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc UMP biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain 387 405 2.1E-66
Gene3D G3DSA:3.40.50.20 1 116 3.7E-50
PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain 211 230 2.1E-66
ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain 171 185 -
SUPERFAMILY SSF52440 IPR016185 Pre-ATP-grasp domain superfamily 1 127 2.59E-51
Pfam PF02142 MGS-like domain IPR011607 Methylglyoxal synthase-like domain 967 1053 1.0E-20
Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. IPR006275 Carbamoyl-phosphate synthase, large subunit 1 1074 13.171
SUPERFAMILY SSF52440 IPR016185 Pre-ATP-grasp domain superfamily 559 677 9.93E-50
Coils Coil 1076 1084 -
SMART SM01096 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain 426 549 1.3E-74
Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. IPR006275 Carbamoyl-phosphate synthase, large subunit 5 1079 13.354
PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain 175 187 2.1E-66
ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain 711 725 -
ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain 849 856 -
PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain 246 263 2.1E-66
SMART SM00851 IPR011607 Methylglyoxal synthase-like domain 966 1053 1.2E-30
PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain 48 58 2.1E-66
ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain 304 311 -
Gene3D G3DSA:3.40.50.1380 IPR036914 Methylglyoxal synthase-like domain superfamily 947 1084 1.2E-36
ProSiteProfiles PS50975 ATP-grasp fold profile. IPR011761 ATP-grasp fold 133 335 42.857
ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile. 1 24 6.0
Gene3D G3DSA:3.40.50.20 556 664 1.4E-48
Gene3D G3DSA:3.30.470.20 119 409 8.0E-129
TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit IPR006275 Carbamoyl-phosphate synthase, large subunit 2 1063 0.0
SUPERFAMILY SSF56059 675 944 1.29E-100
Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain 128 341 1.3E-70
SUPERFAMILY SSF48108 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily 403 556 7.85E-53
Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain 675 886 3.4E-32
ProSiteProfiles PS50975 ATP-grasp fold profile. IPR011761 ATP-grasp fold 680 880 45.729
Gene3D G3DSA:1.10.1030.10 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily 410 555 1.0E-46
ProSiteProfiles PS51855 MGS-like domain profile. 947 1084 28.283
Gene3D G3DSA:3.30.470.20 667 946 3.0E-115
PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain 304 333 2.1E-66
PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain 19 33 2.1E-66
CDD cd01424 MGS_CPS_II IPR033937 Carbamoyl-phosphate synthase large chain, methylglyoxal synthase-like domain 953 1063 4.09595E-39
Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain 429 549 1.1E-38
SUPERFAMILY SSF56059 128 408 2.83E-107
SUPERFAMILY SSF52335 IPR036914 Methylglyoxal synthase-like domain superfamily 946 1082 3.92E-38

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.